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发布时间:2017/3/29 20:54:11  点击量:1101  责任编辑:admin

张国文同志个人简历

 

 

                                       

一、基本情况:

姓   名:  张国文

性   别:  男

职   称:  教授(二级)

学   位:  博士

职   务:  副院长、博士生导师

电   话:  0791-88305234

E-mail: gwzhang@ncu.edu.cn

主要研究领域:食品化学与分析、功能食品与营养、食品质量与安全

高层次人才类型:江西省百千万人才工程人选、江西省高等学校中青年学科带头人


二、个人简历:

1、学习、工作经历:(从大学期间写起)

学习经历:

1983.9—1987.7        江西大学化学系分析化学专业本科生,获学士学位

1987.9—1990.1        江西大学化学系分析化学专业研究生,获硕士学位

2002.9—2005.6        南昌大学食品科学与工程系食品科学与工程专业博士生,获博士学位


工作经历:

1990.3—1993.5        江西工业大学食品工程系,助教

1993.5—1997.6        江西工业大学食品工程系,讲师

1997.6—2002.9        南昌大学生命科学与食品工程学院,副教授

2002.9—2014.7        南昌大学生命科学与食品工程学院,教授,博士生导师

2014.7—             南昌大学食品学院,教授,博士生导师


2、教学情况简介:(指承担本科生和研究生课程)

承担的本科生课程:食品分析、食品分析实验、现代食品检测技术、现代食品检测技术实验、食品科学技术前沿、认识实习、生产实习、毕业实习

承担的研究生课程:高等分析化学、食品科学技术研究进展、营养与食品科学技术研究进展


3、在研项目、科研、课题情况综述:(指本人主要的研究方向)

先后承担国家基金、教育部高校博士点基金、国家重点实验室基金、江西省重大科技项目等20多项国家级和省部级科研项目。

近年承担的部分项目:

(1) 基于化学计量学的合成食品添加剂体外DNA靶向作用检测技术及其作用机制研究(31460422). 国家基金项目, 2015.1-2018.12, 主持.

(2) 具有潜在致癌性的有机氮农药与DNA的相互作用机制(21167013). 国家基金项目, 2012.1-2015.12, 主持.

(3) 几种抗心血管病黄酮化合物与蛋白质的相互作用及典型食物营养物的影响机制(31060210), 国家基金项目, 2011.1-2013.12, 主持.

(4) 几种具有潜在致癌性的人工合成食品添加剂与靶分子DNA的识别机制(20123601110005). 教育部高等学校博士学科点基金项目, 2013.1-2015.12, 主持.

(5) 食品中化学危害因子风险的形成机制及检测新技术研究(20143ACB20006). 江西省重大科技项目, 2015.1-2017.12, 主持.

(6) 山柰酚、桑色素抑制黄嘌呤氧化酶活性的分子机制及其联合抑制行为研究(20142BAB204001). 江西省基金项目, 2014,1-2015.12, 主持.

(7) 蛋白质-多糖对芹菜素的包载、释放及其抑制α-葡萄糖苷酶活性的机制研究(GJJ150187). 江西省教育厅科技项目, 2016.1-2018.12, 主持.

(8) 基于化学计量学的合成食品添加剂DNA靶向作用检测新技术研究(20141BBG70092). 江西省科技支撑项目, 2014,1-2015.12, 主持.

(9) 食品中化学、生物风险因子的作用机理及新检测技术研究(SKLF-ZZA-201302). 国家重点实验室项目, 2013,1-2015.12, 子项目负责人.

(10) 抗癌植物功能因子与蛋白质的相互作用及食物营养物的影响机制(SKLF-TS-200917). 国家重点实验室项目, 2009.1-2010.12, 主持.

(11) 基于光谱特征的农药致突变性筛选新技术研究(2009BNA0900,20112BBF60010). 江西省科技支撑项目, 2009.7-2013.6, 主持.

(12) 抗癌植物活性成分芍药苷、杜鹃素与 DNA 的作用机制及金属离子的扰动行为(20114BAB204019). 江西省基金项目, 2011.1-2013.12, 主持.

(13) 食品中氨基甲酸酯类农药对DNA的损伤作用机理及其关键检测技术(2010BSA17400). 江西省科技支撑项目, 2010,1-2012.12, 主持.


4、代表性专著、论文及专利、获奖等情况:(可详细罗列和评价)

以第一作者或通信作者发表论文200多篇,其中SCI收录80多篇(含ESI高被引论文5篇),h因子23,获得国家级教学成果二等奖2项,江西省教学成果一等奖2项、二等奖2项,江西省自然科学三等奖2项,江西省高等学校科技成果三等奖1项和吉安市科技进步三等奖1项,主编教材4部,获得授权发明专利1项,多次获得江西省优秀硕士学位论文指导教师、南昌大学优秀研究生指导教师等荣誉。

4.1近年代表性论文:

(1) Cen Zhang, Guowen Zhang*, Yijing Liao, Deming Gong. Myricetin inhibits the generation of superoxide anion by reduced form of xanthine oxidase. Food Chemistry, 2017, 221:1569-1577.

(2) Yingying Liu, Guowen Zhang*, Ni Zeng, Song Hu. Interaction between 8-methoxypsoralen and trypsin: Monitoring by spectroscopic, chemometrics and molecular docking approaches. Spectrochimica Acta, Part A, 2017, 173: 188-195

(3) Suyun Lin, Li Zeng, Guowen Zhang*, Yijing Liao, Deming Gong. Synthesis, characterization and xanthine oxidase inhibition of Cu(II)–chrysin complex. Spectrochimica Acta, Part A, 2017, 178:71-78.

(4) Xi Peng, Guowen Zhang*, Yijing Liao, Deming Gong. Inhibitory kinetics and mechanism of kaempferol on α-glucosidase. Food Chemistry, 2016, 190(1): 207-215.  

(5) Mo Tao, Guowen Zhang*, Junhui Pan, Chunhong Xiong. Deciphering the groove binding modes of tau-fluvalinate and flumethrin with calf thymus DNA. Spectrochimica Acta, Part A, 2016, 155(15): 28-37.

(6) Xiaoyue Zhou, Cen Zhang, Guowen Zhang*, Yijing Liao. Intercalation of daphnetin–Cu(II) complex with calf thymus DNA. RSC Advances, 2016, 6: 5408-5418.

(7) Xi Peng, Guowen Zhang*, Li Zeng. Inhibition of α-glucosidase by vitamin D3 and the effect of vitamins B1 and B2. Food & Function, 2016, 7(2): 982-991.

(8) Suyun Lin, Guowen Zhang*, Yijing Liao, Deming Gong. Inhibitory kinetics and mechanism of dietary vitamins D3 and B2 on xanthine oxidase. Food & Function, 2016, 7: 2849-2861.

(9) Li Zeng, Guowen Zhang*, Yijing Liao, Deming Gong. Inhibitory mechanism of morin on α-glucosidase and its anti-glycation properties. Food & Function, 2016, 7: 3953-3963.

(10) Li Zeng, Guowen Zhang*, Suyun Lin, Deming Gong. Inhibitory mechanism of apigenin on α-glucosidase and synergy analysis of flavonoids. Journal of Agricultural and Food Chemistry, 2016, 64 (37):6939–6949.

(11) Cen Zhang, Guowen Zhang*, Junhui Pan, Deming Gong. Galangin competitively inhibits xanthine oxidase by a ping-pong mechanism. Food Research International, 2016, 89: 152-160.

(12) Yaping Wang, Guowen Zhang*, Langhong Wang. Potential toxicity of phthalic acid esters plasticizer: Interaction of dimethyl phthalate with trypsin in vitro. Journal of Agricultural and Food Chemistry, 2015, 63(1):75-84.

(13) Yajie Wang, Guowen Zhang*, Junhui Pan, Deming Gong. Novel insights into the inhibitory mechanism of kaempferol on xanthine oxidase. Journal of Agricultural and Food Chemistry, 2015, 63(2):526-534.

(14) Yue Zhang, Junhui Pan, Guowen Zhang*, Xiaoyue Zhou. Intercalation of herbicide propyzamide into DNA using acridine orange as a fluorescence probe. Sensors & Actuators: B. Chemical, 2015, 206: 630-639.

(15)Xiaoyue Zhou, Guowen Zhang*, Junhui Pan. Groove binding interaction between daphnetin and calf thymus. International Journal of Biological Macromolecules, 2015, 74:185-194.

(16) Suyun Lin, Guowen Zhang*, Yijing Liao, Junhui Pan, Deming Gong. Dietary flavonoids as xanthine oxidase inhibitors: Structure–affinity and structure–activity relationships. Journal of Agricultural and Food Chemistry, 2015, 63(2):7784-7794.

(17) Suyun Lin, Guowen Zhang*, Junhui Pan, Deming Gong. Deciphering the inhibitory mechanism of genistein on xanthine oxidase in vitro. Journal of Photochemistry and Photobiology B: Biology, 2015, 153: 463-472.

(18) Langhong Wang, Mo Tao, Guowen Zhang*, Song Li, Deming Gong. Partial intercalative binding of food colorant erythrosine to herring sperm DNA. RSC Advances, 2015, 5(119): 98366 -98376.

(19) Yu Li, Guowen Zhang*, Junhui Pan, Yue Zhang. Determination of metolcarb binding to DNA by spectroscopic and chemometrics methods with the use of acridine orange as a probe. Sensors & Actuators: B. Chemical, 2014, 191: 464-472.

(20) Jiakai Yan, Guowen Zhang*, Junhui Pan, Yajie Wang. α-Glucosidase inhibition by luteolin: Kinetics, interaction and molecular docking. International Journal of Biological Macromolecules, 2014, 64: 213-223.

(21) Guowen Zhang*, Langhong Wang, Xiaoyue Zhou, Yu Li, Deming Gong. Binding characteristics of sodium saccharin with calf thymus DNA in vitro. Journal of Agricultural and Food Chemistry, 2014, 62(4): 991-1000.

(22) Yajie Wang, Guowen Zhang*, Jiakai Yan, Deming Gong. Inhibitory effect of morin on tyrosinase: Insights from spectroscopic and molecular docking studies. Food Chemistry, 2014, 163: 226-233.

(23) Guowen Zhang*, Yadi Ma. Mechanistic and conformational studies on the interaction of food dye amaranth with human serum albumin by multispectroscopic methods. Food Chemistry, 2013, 136(2): 442-449.

(24)Yaping Wang, Guowen Zhang*, Langhong Wang. Interaction of prometryn to human serum albumin: Insights from spectroscopic and molecular docking studies. Pesticide Biochemistry and Physiology, 2014, 108:66–73.

(25) Xiaoyue Zhou, Guowen Zhang*, Langhong Wang. Probing the binding mode of psoralen to calf thymus DNA. International Journal of Biological Macromolecules, 2014, 67: 228-237.

(26) Guowen Zhang*, Yuting Hu, Junhui Pan. Interaction between toddalolatone and human serum albumin. Journal of Solution Chemistry, 2014, 43(4): 727-745.

(27) Xiaoyue Zhou, Guowen Zhang*, Langhong Wang. Binding of 8-methoxypsoralen to DNA in vitro: Monitoring by Spectroscopic and chemometrics approaches. Journal of Luminescence, 2014, 154: 116-123.

(28) Yu Li, Guowen Zhang*, Mo Tao. Binding properties of herbicide chlorpropham to DNA: Spectroscopic, chemometrics and modeling investigations. Journal of Photochemistry & Photobiology, B: Biology, 2014, 138: 109-117.

(29) Langhong Wang , Guowen Zhang*, Junhui Pan, Chunhong Xiong, Deming Gong. Intercalation binding of food antioxidant butylated hydroxyanisole to calf thymus DNA. Journal of Photochemistry & Photobiology, B: Biology, 2014, 141:253-261.

(30) Yue Zhang, Guowen Zhang*, Yu Li, Yuting Hu. Probing the binding of insecticide permethrin to calf thymus DNA by spectroscopic techniques merging with chemometrics method. Journal of Agricultural and Food Chemistry, 2013, 61(11):2638-2647.

(31) Guowen Zhang*, Peng Fu, Junhui Pan. Multispectroscopic studies of paeoniflorin binding to calf thymus DNA in vitro. Journal of Luminescence, 2013, 134: 303-309.

(32) Guowen Zhang*, Mingming Hu, Li He, Peng Fu, Lin Wang, Jia Zhou. Optimization of microwave-assisted enzymatic extraction of polyphenols from waste peanut shells and evaluation of its antioxidant and antibacterial activities in vitro. Food and Bioproducts Processing, 2013, 91(2):157-167.

(33) Guowen Zhang*, Yepeng Zhang, Yue Zhang, Yu Li. Spectroscopic studies of cyanazine binding to calf thymus DNA with the use of ethidium bromide as a probe. Sensors & Actuators: B. Chemical, 2013,182: 453-460.

(34) Guowen Zhang*, Yadi Ma. Spectroscopic studies on the interaction of sodium benzoate, a food preservative, with calf thymus DNA. Food Chemistry, 2013, 141(1):41-47.

(35) Pan Zhu, Guowen Zhang*, Yadi Ma, Yepeng Zhang, Hong Miao, Yongning Wu. Study of DNA interactions with bifenthrin by spectroscopic techniques and molecular modeling. Spectrochimica Acta A, 2013, 112: 7-14.

(36) Jiakai Yan, Guowen Zhang*, Yuting Hu, Yadi Ma. Effect of luteolin on xanthine oxidase: Inhibition kinetics and interaction mechanism merging with docking simulation. Food Chemistry, 2013, 141(4): 3766-3773.

(37) Yadi Ma, Junhui Pan, Guowen Zhang*, Yue Zhang. Binding properties of butylated hydroxytoluene with calf thymus DNA in vitro. Journal of Photochemistry and Photobiology B: Biology, 2013, 126:112-118.

(38)Yue Zhang, Guowen Zhang*, Xiaoyue Zhou, Yu Li. Determination of acetamiprid partial-intercalative binding to DNA by use of spectroscopic, chemometrics, and molecular docking techniques. Analytical and Bioanalytical Chemistry, 2013, 405(27):8871-8883.

(39) Yadi Ma, Guowen Zhang*, Junhui Pan. Spectroscopic studies of DNA interactions with food colorant indigo carmine with the use of ethidium bromide as a fluorescence probe. Journal of Agricultural and Food Chemistry, 2012, 60(43): 10867-10875.

(40) Guowen Zhang*, Lin Wang, Junhui Pan. Probing the binding of the flavonoid diosmetin to human serum albumin by multispectroscopic techniques. Journal of Agricultural and Food Chemistry, 2012, 60(10): 2721-2729.

(41) Guowen Zhang*, Yadi Ma, Lin Wang, Yepeng Zhang, Jia Zhou. Multispectroscopic studies on the interaction of maltol, a food additive, with bovine serum albumin. Food Chemistry, 2012, 133(2):264-270.

(42) Guowen Zhang*, Xing Hu, Peng Fu. Spectroscopic studies on the interaction between carbaryl and calf thymus DNA with the use of ethidium bromide as a fluorescence probe. Journal of Photochemistry & Photobiology, B: Biology, 2012, 108: 53-61.

(43) Yepeng Zhang, Guowen Zhang*, Peng Fu, Yadi Ma, Jia Zhou. Study on the interaction of triadimenol with calf thymus DNA by multispectroscopic methods and molecular modeling. Spectrochimica Acta, Part A, 2012, 96: 1012-1019.

(44) Guowen Zhang*, Peng Fu, Lin Wang, Mingming Hu. Molecular spectroscopic studies of farrerol interaction with calf thymus DNA. Journal of Agricultural and Food Chemistry, 2011, 59(16): 8944-8952.

(45) Guowen Zhang*, Li He, Mingming Hu. Optimized ultrasonic-assisted extraction of flavonoids from prunella vulgaris L. and evaluation of antioxidant activities in vitro. Innovative Food Science and Emerging Technologies, 2011, 12(1): 18-25.  

4.2 获奖情况:

(1) 食品科学与工程专业创新人才培养体系的构建与实践. 国家级教学成果二等奖, 2014年9月.

(2) 理工结合型人才培养模式研究与实践. 国家级教学成果二等奖, 1997年10月.

(3)《食品化学》精品课程建设的探索与实践, 江西省教学成果一等奖, 2010年10月.

(4) 理工结合型人才培养模式研究与实践, 江西省教学成果一等奖, 1997年3月.

(5) 化学计量学在复杂光谱解析中的应用. 江西省自然科学三等奖, 2008年3月.

(6) 中国(江西)茶叶化学成分与营养保健功能的研究. 江西省自然科学三等奖, 2005年4月.

(7) 化学计量学在食品安全与检测中的应用. 江西省高等学校科技成果三等奖, 2007年8月.

(8) 金桔低产园改造及系列产品加工. 吉安市科技进步三等奖, 2002年3月.

(9) 强化学院教学管理,提高学院专业建设及人才培养质量, 江西省教学成果二等奖, 2008年12月.

(10) 工科专业学位研究生培养模式的改革与实践,江西省教学成果二等奖, 2015年1月.

(11) 获2013、2014、2015年江西省优秀硕士论文指导老师.

(12) 获2008—2011年南昌大学优秀研究生指导教师奖.

(13) 获2011年度南昌大学“江铃奖教金”.

(14) 获2008年度南昌大学“教书育人先进个人”.

(15) 获2005年和2009年南昌大学“中兴发展奖教金”.





 

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E-mail:food@ncu.edu.cn